ABSTRACT
Objective:To observe the clinical efficacy of Zhibitai capsule in the treatment of dyslipidemia with phlegm-stasis binding pattern, in order to evaluate its effectiveness and safety. Method:Totally 82 patients of dyslipidemia with phlegm-stasis binding pattern were selected from the outpatient department of internal medicine in Hospital of Xidian University from July 2018 to July 2019. According to the random number table method, they were divided into control group and observation group, with41 cases in each group. Control group was treated with aAtorvastatin calcium, and observation group was treated with Zhibitai capsules. The changes in blood lipid index, liver function and renal function were measured before and after 8-week treatment in two groups, the efficacy on traditional Chinese medicine (TCM) syndromes and clinical symptom scores before and after treatment were compared between two groups, and the adverse reactions, such as liver pain and muscle pain, were recorded among patients. Result:The changes of blood lipids were compared after 8 weeks of treatment, total cholesterol (TC), triglyceride (TG), and low-density lipoprotein cholesterol (LDL-C) were all lower than before, while high-density lipoprotein cholesterol (HDL-C) was increased (P<0.05), the total effective rate in control group was 90.24% (37/41), which was 92.68% (38/41) in observation group, with no significant difference between two groups, in the TCM syndrome scores of two groups before and after treatment, four common TCM syndromes, namely scores dizziness, chest tightness, head heavy as if swathed and chest fullness, were decreased (P<0.05). In terms of the efficacy of two groups of TCM syndromes, the total effective rate in control group was 87.80% (36/41), which was 92.68% (38/41) in observation group, with no statistically significant difference between two groups. Control group had 3 cases of increased transaminase, but none of them beyond 2 times of the normal upper limit, and observation group had 1 case of mild abdominal distension and nausea, which did not affect continued medication. No muscle pain or liver pain occurred in two groups. Conclusion:Zhibitai capsule is effective in treating dyslipidemia, which is comparable to atorvastatin calcium in treating dyslipidemia, with the safety and reliability.
ABSTRACT
@#Objective To explore the epidemiological characteristics and influencing factors of fall of elderly aged ≥ 60 years in Guangzhou from 2014 to 2018 ，so as to provide evidence for effective prevention and control measures． Methods Data on fall of the elderly was collected from the first diagno- sis in injury surveillance hospitals in Guangzhou from 2014 to 2018，and distribution description and epi- demiological analysis were adopted． Ｒesults 9 503 cases of fall of the elderly were reported in 5 injury surveillance hospitals，accounting for 49．41% of injuries in the elderly，and had occupied the first place in the cause of injury in 5 consecutive years． The sex ratio of men to women was 1 ∶ 1．67． Most of the patients had a primary or junior school degree，high rate in October-December，mainly occurred at home when doing leisure activities or life activities． The fall mainly led to injuries of head or lower extremities， contributed to contusion /bruise or fracture． And most of them were mild and moderate injury． Logistic re- gression showed that female，old age，high educational level，December to February，at home，walking， leisure activities and life activities were risk factors for falling among the elderly in Guangzhou ( all P ＜ 0．001) ． Conclusions Fall is the primary cause of injuries to the elderly in Guangzhou，especially the elderly female population． The targeted prevention and intervention measures should be developed ac- cording to their distribution characteristics．
ABSTRACT
It clearly defined 41 administrative fees would be canceled or suspend in China since April 1,2017.Of which,there were 3 projects involved in the center for disease control(CDC).Canceling these three charges brought impact on enterprises,individuals and CDCs.It suggested that the related department should pay attention to it,establish and improve these three measures to eliminate fees,guide and encourage CDCs to provide professional services to outside world,which would promote the healthy development of the real economy and CDCs.